Steroid treatment is routinely given for patients with inner ear disorders, such as unremitting Meniere's disease or idiopathic sudden sensorineural hearing loss ISSNHL. However, for some patients, systemic steroids may be unsuccessful or contraindicated; therefore, intratympanic steroid ITS administration may be a suitable alternative for rapid symptom control. ITS is increasingly used as a treatment for inner ear disease. It is generally well-tolerated, has been shown to result in superior perilymph concentration of steroids without the risk of systemic side effects, and so can be used as an alternative or in addition to systemic steroid use.
Idiopathic sudden sensorineural hearing loss ISSNHL , considered an otological emergency, is defined as deafness of cochlear or retrocochlear origin within 72 hours, affecting at least 3 consecutive frequencies by 30 dB or greater with no identifiable cause. Piccirillo, M. Louis, in an accompanying editorial. Nevertheless, for patients with sudden hearing loss who are thought to be at too high a risk for systemic steroid usage, this study suggests a reasonable alternative in the setting of rapid specialty referral.
Additional research should focus on identifying subgroups of patients for whom steroid treatment seems especially helpful and whether combination oral and intratympanic is better than single modality alone. However, the study by Rauch et al did not answer the lingering question of whether there is any benefit of steroids for the patient with sudden sensorineural hearing loss. A better understanding of the pathophysiology of hearing loss, identification of unique prognostic subgroups, and adherence to rigorous clinical research methods are required for the proper assessment of the therapeutic benefits of existing treatments and discovery of new treatments for this disorder.
Note: Content may be edited for style and length. Science News. Journal References : S. Rauch, C. Halpin, P. Antonelli, S. Babu, J. Carey, B. Gantz, J. Goebel, P. Hammerschlag, J. Harris, B. Isaacson, D. Lee, C. Linstrom, L. Parnes, H. Shi, W. Slattery, S. Telian, J. Vrabec, D. ScienceDaily, 25 May Injection therapy for sudden hearing loss disorder may be suitable alternative to oral steroids.
Retrieved August 11, from www. The study is the first
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