Equal or greater consideration should be given to diet, calcium balance, physiotherapy, and good general health promoting measures. The FDA's Endocrinologic and Metabolic Drugs Advisory Committee considered the data submitted for osteoporosis in two meetings held and the data for aplastic anemia in In April , the FDA announced that the data was not sufficient, and withdrew the marketing authority for stanozolol for senile and postmenopausal osteoporosis and for raising hemoglobin levels in aplastic anemia.
Sanofi had stanozolol manufactured in the US by Searle , which stopped making the drug in October In , Lundbeck withdrew stanozolol from the market in the US; as of no other company is marketing stanozolol as a pharmaceutical drug in the US but it can be obtained via a compounding pharmacy. Pfizer had marketed stanozolol as a veterinary drug; in Pfizer spun off its veterinary business to Zoetis  and in Pfizer transferred the authorizations to market injectable and tablet forms of stanozolol as a veterinary drug to Zoetis.
It is used in veterinary medicine as an adjunct in the management of wasting diseases, to stimulate the formation of red blood cells , arouse appetite, and promote weight gain, but the evidence for these uses is weak.
It is used as a performance-enhancing drug in race horses. Its side effects include weight gain, water retention, and difficulty eliminating nitrogen-based waste products and it is toxic to the liver, especially in cats. Because it may promote the growth of tumors, it is contraindicated in dogs with enlarged prostates. Stanozolol and other AAS were commonly used to treat hereditary angioedema attacks, until several drugs were brought to market specifically for treatment of that disease, the first in Cinryze , Berinert , ecallantide Kalbitor , icatibant Firazyr and Ruconest.
Brand names under which stanozolol is or has been marketed include Anaysynth, Menabol, Neurabol Caps. The tradename Anabol should not be confused with Anabiol. Stanozolol and other synthetic steroids were first banned by the International Olympic Committee and the International Association of Athletics Federations in , after methods to detect them had been developed.
Stanozolol is especially widely used by the athletes from post-Soviet countries. Stanozolol has been investigated in the treatment of a number of dermatological conditions including urticaria , hereditary angioedema , Raynaud's phenomenon , cryofibrinogenemia , and lipodermatosclerosis. From Wikipedia, the free encyclopedia. Discontinued steroid for heart treatment.
Not to be confused with Stanolone , Stanozide , or Winstan. IUPAC name. DB Y. D Y. Interactive image. The examples and perspective in this article deal primarily with the United States and do not represent a worldwide view of the subject.
You may improve this article , discuss the issue on the talk page , or create a new article , as appropriate. January Learn how and when to remove this template message. Doping in Sports. ISBN The oral form is marketed for human use whereas an aqueous suspension for injection is used in the veterinary field.
The American Journal of Emergency Medicine. PMID This case is important as stanozolol misuse is relatively common, due to its high oral bioavailability and perceived safety profile compared with other parenteral AAS. Handbook of Veterinary Pharmacology. Molecular Nutrition Llc. Retrieved Horse Racing". The Horse.
British Medical Journal. PMC The Journal of Allergy and Clinical Immunology. Medicine and Science in Sports and Exercise. British Journal of Pharmacology. Ellis Horwood. Academic Press. Wolters Kluwer Health. Testosterone has low oral bioavailability with only about half of an oral dose available after hepatic first-pass metabolism.
Some analogues of testosterone e. Journal of Chromatography. October S2CID Disposition of Toxic Drugs and Chemicals in Man 8th ed. The Journal of New Drugs. The Kefauver-Harris Drug Amendments. Food and Drug Administration. Pharmacy Today. United States Food and Drug Administration.
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